AP IMPACT: Big Pharma cashes in on HGH abuse


A federal crackdown on illicit foreign supplies of human growth hormone has failed to stop rampant misuse, and instead has driven record sales of the drug by some of the world's biggest pharmaceutical companies, an Associated Press investigation shows.


The crackdown, which began in 2006, reduced the illegal flow of unregulated supplies from China, India and Mexico.


But since then, Big Pharma has been satisfying the steady desires of U.S. users and abusers, including many who take the drug in the false hope of delaying the effects of aging.


From 2005 to 2011, inflation-adjusted sales of HGH were up 69 percent, according to an AP analysis of pharmaceutical company data collected by the research firm IMS Health. Sales of the average prescription drug rose just 12 percent in that same period.


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EDITOR'S NOTE — Whether for athletics or age, Americans from teenagers to baby boomers are trying to get an edge by illegally using anabolic steroids and human growth hormone, despite well-documented risks. This is the second of a two-part series.


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Unlike other prescription drugs, HGH may be prescribed only for specific uses. U.S. sales are limited by law to treat a rare growth defect in children and a handful of uncommon conditions like short bowel syndrome or Prader-Willi syndrome, a congenital disease that causes reduced muscle tone and a lack of hormones in sex glands.


The AP analysis, supplemented by interviews with experts, shows too many sales and too many prescriptions for the number of people known to be suffering from those ailments. At least half of last year's sales likely went to patients not legally allowed to get the drug. And U.S. pharmacies processed nearly double the expected number of prescriptions.


Peddled as an elixir of life capable of turning middle-aged bodies into lean machines, HGH — a synthesized form of the growth hormone made naturally by the human pituitary gland — winds up in the eager hands of affluent, aging users who hope to slow or even reverse the aging process.


Experts say these folks don't need the drug, and may be harmed by it. The supposed fountain-of-youth medicine can cause enlargement of breast tissue, carpal tunnel syndrome and swelling of hands and feet. Ironically, it also can contribute to aging ailments like heart disease and Type 2 diabetes.


Others in the medical establishment also are taking a fat piece of the profits — doctors who fudge prescriptions, as well as pharmacists and distributors who are content to look the other way. HGH also is sold directly without prescriptions, as new-age snake oil, to patients at anti-aging clinics that operate more like automated drug mills.


Years of raids, sports scandals and media attention haven't stopped major drugmakers from selling a whopping $1.4 billion worth of HGH in the U.S. last year. That's more than industry-wide annual gross sales for penicillin or prescription allergy medicine. Anti-aging HGH regimens vary greatly, with a yearly cost typically ranging from $6,000 to $12,000 for three to six self-injections per week.


Across the U.S., the medication is often dispensed through prescriptions based on improper diagnoses, carefully crafted to exploit wiggle room in the law restricting use of HGH, the AP found.


HGH is often promoted on the Internet with the same kind of before-and-after photos found in miracle diet ads, along with wildly hyped claims of rapid muscle growth, loss of fat, greater vigor, and other exaggerated benefits to adults far beyond their physical prime. Sales also are driven by the personal endorsement of celebrities such as actress Suzanne Somers.


Pharmacies that once risked prosecution for using unauthorized, foreign HGH — improperly labeled as raw pharmaceutical ingredients and smuggled across the border — now simply dispense name brands, often for the same banned uses. And usually with impunity.


Eight companies have been granted permission to market HGH by the U.S. Food and Drug Administration, which reviews the benefits and risks of new drug products. By contrast, three companies are approved for the diabetes drug insulin.


The No. 1 maker, Roche subsidiary Genentech, had nearly $400 million in HGH sales in the U.S. last year, up an inflation-adjusted two-thirds from 2005. Pfizer and Eli Lilly were second and third with $300 million and $220 million in sales, respectively, according to IMS Health. Pfizer now gets more revenue from its HGH brand, Genotropin, than from Zoloft, its well-known depression medicine that lost patent protection.


On their face, the numbers make no sense to the recognized hormone doctors known as endocrinologists who provide legitimate HGH treatment to a small number of patients.


Endocrinologists estimate there are fewer than 45,000 U.S. patients who might legitimately take HGH. They would be expected to use roughly 180,000 prescriptions or refills each year, given that typical patients get three months' worth of HGH at a time, according to doctors and distributors.


Yet U.S. pharmacies last year supplied almost twice that much HGH — 340,000 orders — according to AP's analysis of IMS Health data.


While doctors say more than 90 percent of legitimate patients are children with stunted growth, 40 percent of 442 U.S. side-effect cases tied to HGH over the last year involved people age 18 or older, according to an AP analysis of FDA data. The average adult's age in those cases was 53, far beyond the prime age for sports. The oldest patients were in their 80s.


Some of these medical records even give explicit hints of use to combat aging, justifying treatment with reasons like fatigue, bone thinning and "off-label," which means treatment of an unapproved condition


Even Medicare, the government health program for older Americans, allowed 22,169 HGH prescriptions in 2010, a five-year increase of 78 percent, according to data released by the Centers for Medicare and Medicaid Services in response to an AP public records request.


"There's no question: a lot gets out," said hormone specialist Dr. Mark Molitch of Northwestern University, who helped write medical standards meant to limit HGH treatment to legitimate patients.


And those figures don't include HGH sold directly by doctors without prescriptions at scores of anti-aging medical practices and clinics around the country. Those numbers could only be tallied by drug makers, who have declined to say how many patients they supply and for what conditions.


First marketed in 1985 for children with stunted growth, HGH was soon misappropriated by adults intent on exploiting its modest muscle- and bone-building qualities. Congress limited HGH distribution to the handful of rare conditions in an extraordinary 1990 law, overriding the generally unrestricted right of doctors to prescribe medicines as they see fit.


Despite the law, illicit HGH spread around the sports world in the 1990s, making deep inroads into bodybuilding, college athletics, and professional leagues from baseball to cycling. The even larger banned market among older adults has flourished more recently.


FDA regulations ban the sale of HGH as an anti-aging drug. In fact, since 1990, prescribing it for things like weight loss and strength conditioning has been punishable by 5 to 10 years in prison.


Steve Kleppe, of Scottsdale, Ariz., a restaurant entrepreneur who has taken HGH for almost 15 years to keep feeling young, said he noticed a price jump of about 25 percent after the block on imports. He now buys HGH directly from a doctor at an annual cost of about $8,000 for himself and the same amount for his wife.


Many older patients go for HGH treatment to scores of anti-aging practices and clinics heavily concentrated in retirement states like Florida, Nevada, Arizona and California.


These sites are affiliated with hundreds of doctors who are rarely endocrinologists. Instead, many tout certification by the American Board of Anti-Aging and Regenerative Medicine, though the medical establishment does not recognize the group's bona fides.


The clinics offer personalized programs of "age management" to business executives, affluent retirees, and other patients of means, sometimes coupled with the amenities of a vacation resort. The operations insist there are few, if any, side effects from HGH. Mainstream medical authorities say otherwise.


A 2007 review of 31 medical studies showed swelling in half of HGH patients, with joint pain or diabetes in more than a fifth. A French study of about 7,000 people who took HGH as children found a 30 percent higher risk of death from causes like bone tumors and stroke, stirring a health advisory from U.S. authorities.


For proof that the drug works, marketers turn to images like the memorable one of pot-bellied septuagenarian Dr. Jeffry Life, supposedly transformed into a ripped hulk of himself by his own program available at the upscale Las Vegas-based Cenegenics Elite Health. (He declined to be interviewed.)


These promoters of HGH say there is a connection between the drop-off in growth hormone levels through adulthood and the physical decline that begins in late middle age. Replace the hormone, they say, and the aging process slows.


"It's an easy ruse. People equate hormones with youth," said Dr. Tom Perls, a leading industry critic who does aging research at Boston University. "It's a marketing dream come true."


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Associated Press Writer David B. Caruso reported from New York and AP National Writer Jeff Donn reported from Plymouth, Mass. AP Writer Troy Thibodeaux provided data analysis assistance from New Orleans.


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AP's interactive on the HGH investigation: http://hosted.ap.org/interactives/2012/hgh


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The AP National Investigative Team can be reached at investigate(at)ap.org


EDITOR'S NOTE _ Whether for athletics or age, Americans from teenagers to baby boomers are trying to get an edge by illegally using anabolic steroids and human growth hormone, despite well-documented risks. This is the second of a two-part series.


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Boehner's Take on Fiscal Cliff Deal: 'God Only Knows'


Dec 21, 2012 11:00am







Speaker of the House John Boehner bluntly acknowledged Friday morning he did not have the votes to pass his “Plan B” and said the only real solution is a broad agreement to cut spending and reform the tax code. Then he added these words:


“How we get there, God only knows.”


That about sums up the whole “fiscal cliff” situation after a chaotic Thursday night when Republicans had to abandon “Plan B” – their proposal to raise taxes only on people making more than $1 million.


Boehner said he is not giving up on talks to pursue a bipartisan agreement with the President, who wants taxes to be raised on people making more than $250,000. But Boehner made it clear nothing is going on right now.  Instead he said it was up to Senate Democrats and the White House to make the next move.


Read more  about “Plan B” and the dramatic action in the House on Thursday.





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Football: Newcastle powerless to keep Ba admits Pardew






LONDON: Newcastle manager Alan Pardew admitted on Thursday that his club are powerless to keep Demba Ba if the Senegal striker wants to quit St James' Park.

Ba has a clause in his contract that allows him to leave if another team offers 7.5 million pounds and Pardew knows the former West Ham star could attract interest from several clubs during the January transfer window.

The 27-year-old, who has scored 11 times this season, was forced to deny reports this week that he had said it would be a dream come true to join Arsenal, while Liverpool are also said to be interested.

In the circumstances, Pardew is resigned to a month of worrying that one of his key players will be tempted away from Tyneside.

"It's unfortunate that the contract he has leaves open a lot of questions because we have this clause and every window that comes around, I have to answer the same questions," Pardew said.

"It would be disappointing for him to leave in this window for this club and for his team-mates here, but the decision will be his, ultimately, because that clause is there.

"The most important things we have got with Demba is he is someone who is a goalscorer and he is scoring goals, and that's very, very important to a side.

"His commitment to and work-rate for the team, I don't fault."

- AFP/fa



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UP has maximum MLAs facing charges of crimes against women

LUCKNOW: Uttar Pradesh(UP) not only tops in crime rate and politicians with criminal record, it also has maximum number of members of legislative assembly(MLAs) facing charges of crimes against women, including rape.

Total 42 MLAs taken together from all the states of the country have declared charges of crimes against women in their sworn affidavits submitted with the Election Commission of India (ECI) at the time of election. Of these, maximum 12 MLAs are from UP follwed by and West Bengal with seven MLAs each, reveals a study conducted by the Association of Democratic Reforms(ADR), an umbrella body of civil society organisations working for probity and transparency in politics. The study is based on the details provided by the MLAs and MPs to ECI while filing their nomination for the elections.

In UP, six MLAs have declared rape charges pending against them. Of these six, four are from UP, which include three from the ruling Samajwadi Party (SP) and one from Bahujan Samaj Party(BSP). The SP MLAs include Guddu Pandit (MLA from Debai), Anoop Sanda(Sultanpur) and Manoj Kumar Paras(Nagina). BSP MLA, Aleem Khan from Bulandshahr, is also facing rape charges. The two MLAs facing similar charge from other states are Bhartiya Janta Party's Jethabhai G Ahir from Gujarat and Telgu Desham Party's Kandikunta Venkata Prasad from Andhra Pradesh.

Other than these six MLAs, there are 36 MLAs who have declared that they have other charges of crimes against women such as outraging the modesty of a woman, assault, insulting the modesty of a woman etc. Of these 36 MLAs, six are from Congress, five from BJP and three from SP. Further, two Members of Parliament(MPs), Semmalai S of ADMK from the Salem constituency in Tamil Nadu and Adhikari Suvendu of AITC from the Tamluk constituency in West Bengal, have declared that they have charges of crimes against women, such as cruelty and intent to outrage a woman's modesty etc.

Around 287 candidates, who have declared that they have charges of crime against women, contested legislative assembly elections held in the last five years in various states. The charges include rape, outraging the modesty of a woman, assault, insulting the modesty of a woman etc— 72 candidates were independent, 24 were given tickets by the BJP, 26 candidates were fielded by the Congress, the BSP gave tickets to 18 and the SP to 16. Maximum number of such candidates contesting elections were from Maharasthra(41), followed by Uttar Pradesh(37) and West Bengal(22).

Further, around 27 candidates who declared that they have been charged with rape, ten were from UP and five from Bihar. In UP, while SP gave tickets to five candidates facing rape charges, BJP and BSP fielded two each. However, of total twenty-seven, six won the elections, of which four are from UP.

In the 2009 Lok Sabha elections, political parties had given tickets to six candidates who declared that they have been charged with rape. Of these, one each were from RPP, RCP, BSP, JMM and two were independent candidates. Out six candidates facing rape charges, three were from Bihar, one each from Delhi, UP and Andhra Pradesh.

Apart from these six candidates with rape charges, 34 other contesting candidates in 2009 declared that they have charges of crimes against women. Maximum cases of crimes against women are against candidates from Bihar(9), followed by Maharashtra(6) and UP(5).

The ADR has strongly recommend that political parties should stop giving tickets to candidates with criminal backgrounds and who have been charged with serious crimes like murder, attempt to murder, especially crimes against women such as rape.

It also said that on one hand parties condemn crime against women while speaking in the parliament but on the other by giving tickets to candidates who have been charged with crimes against women, particularly rape, they parties in a way have been abetting crime. Candidates with a criminal background should be debarred from contesting elections and political parties should be forced to disclose the criteria on which candidates are given tickets. Cases against MPs and MLAs should be fast tracked and decided upon in a time bound manner.

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AP IMPACT: Steroids loom in major-college football


WASHINGTON (AP) — With steroids easy to buy, testing weak and punishments inconsistent, college football players are packing on significant weight — 30 pounds or more in a single year, sometimes — without drawing much attention from their schools or the NCAA in a sport that earns tens of billions of dollars for teams.


Rules vary so widely that, on any given game day, a team with a strict no-steroid policy can face a team whose players have repeatedly tested positive.


An investigation by The Associated Press — based on dozens of interviews with players, testers, dealers and experts and an analysis of weight records for more than 61,000 players — revealed that while those running the multibillion-dollar sport believe the problem is under control, that is hardly the case.


___


EDITOR'S NOTE — Whether for athletics or age, Americans from teenagers to baby boomers are trying to get an edge by illegally using anabolic steroids and human growth hormone, despite well-documented risks. This is the first of a two-part series.


___


The sport's near-zero rate of positive steroids tests isn't an accurate gauge among college athletes. Random tests provide weak deterrence and, by design, fail to catch every player using steroids. Colleges also are reluctant to spend money on expensive steroid testing when cheaper ones for drugs like marijuana allow them to say they're doing everything they can to keep drugs out of football.


"It's nothing like what's going on in reality," said Don Catlin, an anti-doping pioneer who spent years conducting the NCAA's laboratory tests at UCLA. He became so frustrated with the college system that it drove him in part to leave the testing industry to focus on anti-doping research.


Catlin said the collegiate system, in which players often are notified days before a test and many schools don't even test for steroids, is designed to not catch dopers. That artificially reduces the numbers of positive tests and keeps schools safe from embarrassing drug scandals.


While other major sports have been beset by revelations of steroid use, college football has operated with barely a whiff of scandal. Between 1996 and 2010 — the era of Barry Bonds, Mark McGwire, Marion Jones and Lance Armstrong — the failure rate for NCAA steroid tests fell even closer to zero from an already low rate of less than 1 percent.


The AP's investigation, drawing upon more than a decade of official rosters from all 120 Football Bowl Subdivision teams, found thousands of players quickly putting on significant weight, even more than their fellow players. The information compiled by the AP included players who appeared for multiple years on the same teams, making it the most comprehensive data available.


For decades, scientific studies have shown that anabolic steroid use leads to an increase in body weight. Weight gain alone doesn't prove steroid use, but very rapid weight gain is one factor that would be deemed suspicious, said Kathy Turpin, senior director of sport drug testing for the National Center for Drug Free Sport, which conducts tests for the NCAA and more than 300 schools.


Yet the NCAA has never studied weight gain or considered it in regard to its steroid testing policies, said Mary Wilfert, the NCAA's associate director of health and safety. She would not speculate on the cause of such rapid weight gain.


The NCAA attributes the decline in positive tests to its year-round drug testing program, combined with anti-drug education and testing conducted by schools.


"The effort has been increasing, and we believe it has driven down use," Wilfert said.


Big gains, data show


The AP's analysis found that, regardless of school, conference and won-loss record, many players gained weight at exceptional rates compared with their fellow athletes and while accounting for their heights. The documented weight gains could not be explained by the amount of money schools spent on weight rooms, trainers and other football expenses.


Adding more than 20 or 25 pounds of lean muscle in a year is nearly impossible through diet and exercise alone, said Dan Benardot, director of the Laboratory for Elite Athlete Performance at Georgia State University.


The AP's analysis corrected for the fact that players in different positions have different body types, so speedy wide receivers weren't compared to bulkier offensive tackles. It could not assess each player's physical makeup, such as how much weight gain was muscle versus fat, one indicator of steroid use. In the most extreme case in the AP analysis, the probability that a player put on so much weight compared with other players was so rare that the odds statistically were roughly the same as an NFL quarterback throwing 12 passing touchdowns or an NFL running back rushing for 600 yards in one game.


In nearly all the rarest cases of weight gain in the AP study, players were offensive or defensive linemen, hulking giants who tower above 6-foot-3 and weigh 300 pounds or more. Four of those players interviewed by the AP said that they never used steroids and gained weight through dramatic increases in eating, up to six meals a day. Two said they were aware of other players using steroids.


"I just ate. I ate 5-6 times a day," said Clint Oldenburg, who played for Colorado State starting in 2002 and for five years in the NFL. Oldenburg's weight increased over four years from 212 to 290, including a one-year gain of 53 pounds, which he attributed to diet and two hours of weight lifting daily. "It wasn't as difficult as you think. I just ate anything."


Oldenburg told the AP he was surprised at the scope of steroid use in college football, even in Colorado State's locker room. "College performance enhancers were more prevalent than I thought," he said. "There were a lot of guys even on my team that were using." He declined to identify any of them.


The AP found more than 4,700 players — or about 7 percent of all players — who gained more than 20 pounds overall in a single year. It was common for the athletes to gain 10, 15 and up to 20 pounds in their first year under a rigorous regimen of weightlifting and diet. Others gained 25, 35 and 40 pounds in a season. In roughly 100 cases, players packed on as much 80 pounds in a single year.


In at least 11 instances, players that AP identified as packing on significant weight in college went on to fail NFL drug tests. But pro football's confidentiality rules make it impossible to know for certain which drugs were used and how many others failed tests that never became public.


What is bubbling under the surface in college football, which helps elite athletes gain unusual amounts of weight? Without access to detailed information about each player's body composition, drug testing and workout regimen, which schools do not release, it's impossible to say with certainty what's behind the trend. But Catlin has little doubt: It is steroids.


"It's not brain surgery to figure out what's going on," he said. "To me, it's very clear."


Football's most infamous steroid user was Lyle Alzado, who became a star NFL defensive end in the 1970s and '80s before he admitted to juicing his entire career. He started in college, where the 190-pound freshman gained 40 pounds in one year. It was a 21 percent jump in body mass, a tremendous gain that far exceeded what researchers have seen in controlled, short-term studies of steroid use by athletes. Alzado died of brain cancer in 1992.


The AP found more than 130 big-time college football players who showed comparable one-year gains in the past decade. Students posted such extraordinary weight gains across the country, in every conference, in nearly every school. Many of them eclipsed Alzado and gained 25, 35, even 40 percent of their body mass.


Even though testers consider rapid weight gain suspicious, in practice it doesn't result in testing. Ben Lamaak, who arrived at Iowa State in 2006, said he weighed 225 pounds in high school and 262 pounds in the summer of his freshman year on the Cyclones football team. A year later, official rosters showed the former basketball player from Cedar Rapids weighed 306, a gain of 81 pounds since high school. He graduated as a 320-pound offensive lineman and said he did it all naturally.


"I was just a young kid at that time, and I was still growing into my body," he said. "It really wasn't that hard for me to gain the weight. I had fun doing it. I love to eat. It wasn't a problem."


In addition to random drug testing, Iowa State is one of many schools that have "reasonable suspicion" testing. That means players can be tested when their behavior or physical symptoms suggest drug use.


Despite gaining 81 pounds in a year, Lamaak said he was never singled out for testing.


The associate athletics director for athletic training at Iowa State, Mark Coberley, said coaches and trainers use body composition, strength data and other factors to spot suspected cheaters. Lamaak, he said, was not suspicious because he gained a lot of "non-lean" weight.


"There are a lot of things that go into trying to identify whether guys are using performance-enhancing drugs," Coberley said. "If anybody had the answer, they'd be spotting people that do it. We keep our radar up and watch for things that are suspicious and try to protect the kids from making stupid decisions."


There's no evidence that Lamaak's weight gain was anything but natural. Gaining fat is much easier than gaining muscle. But colleges don't routinely release information on how much of the weight their players gain is muscle, as opposed to fat. Without knowing more, said Benardot, the expert at Georgia State, it's impossible to say whether large athletes were putting on suspicious amounts of muscle or simply obese, which is defined as a body mass index greater than 30.


Looking solely at the most significant weight gainers also ignores players like Bryan Maneafaiga.


In the summer of 2004, Maneafaiga was an undersized 180-pound running back trying to make the University of Hawaii football team. Twice — once in pre-season and once in the fall — he failed school drug tests, showing up positive for marijuana use. What surprised him was that the same tests turned up negative for steroids.


He'd started injecting stanozolol, a steroid, in the summer to help bulk up to a roster weight of 200 pounds. Once on the team, where he saw only limited playing time, he'd occasionally inject the milky liquid into his buttocks the day before games.


"Food and good training will only get you so far," he told the AP recently.


Maneafaiga's coach, June Jones, meanwhile, said none of his players had tested positive for doping since he took over the team in 1999. He also said publicly that steroids had been eliminated in college football: "I would say 100 percent," he told The Honolulu Advertiser in 2006.


Jones said it was news to him that one of his players had used steroids. Jones, who now coaches at Southern Methodist University, said many of his former players put on bulk working hard in the weight room. For instance, adding 70 pounds over a three- to four-year period isn't unusual, he said.


Jones said a big jump in muscle year-over-year — say 40 pounds — would be a "red light that something is not right."


Jones, a former NFL head coach, said he is unaware of any steroid use at SMU and believes the NCAA is doing a good job testing players. "I just think because the way the NCAA regulates it now that it's very hard to get around those tests," he said.


The cost of testing


While the use of drugs in professional sports is a question of fairness, use among college athletes is also important as a public policy issue. That's because most top-tier football teams are from public schools that benefit from millions of dollars each year in taxpayer subsidies. Their athletes are essentially wards of the state. Coaches and trainers — the ones who tell players how to behave, how to exercise and what to eat — are government employees.


Then there are the health risks, which include heart and liver problems and cancer.


On paper, college football has a strong drug policy. The NCAA conducts random, unannounced drug testing and the penalties for failure are severe. Players lose an entire year of eligibility after a first positive test. A second offense means permanent ineligibility from sports.


In practice, though, the NCAA's roughly 11,000 annual tests amount to just a fraction of all athletes in Division I and II schools. Exactly how many tests are conducted each year on football players is unclear because the NCAA hasn't published its data for two years. And when it did, it periodically changed the formats, making it impossible to compare one year of football to the next.


Even when players are tested by the NCAA, people involved in the process say it's easy enough to anticipate the test and develop a doping routine that results in a clean test by the time it occurs. NCAA rules say players can be notified up to two days in advance of a test, which Catlin says is plenty of time to beat a test if players have designed the right doping regimen. By comparison, Olympic athletes are given no notice.


"Everybody knows when testing is coming. They all know. And they know how to beat the test," Catlin said, adding, "Only the really dumb ones are getting caught."


Players are far more likely to be tested for drugs by their schools than by the NCAA. But while many schools have policies that give them the right to test for steroids, they often opt not to. Schools are much more focused on street drugs like cocaine and marijuana. Depending on how many tests a school orders, each steroid test can cost $100 to $200, while a simple test for street drugs might cost as little as $25.


When schools call and ask about drug testing, the first question is usually, "How much will it cost," Turpin said.


Most schools that use Drug Free Sport do not test for anabolic steroids, Turpin said. Some are worried about the cost. Others don't think they have a problem. And others believe that since the NCAA tests for steroids their money is best spent testing for street drugs, she said.


Wilfert, the NCAA official, said the possibility of steroid testing is still a deterrent, even at schools where it isn't conducted.


"Even though perhaps those institutional programs are not including steroids in all their tests, they could, and they do from time to time," she said. "So, it is a kind of deterrence."


For Catlin, one of the most frustrating things about running the UCLA testing lab was getting urine samples from schools around the country and only being asked to test for cocaine, marijuana and the like.


"Schools are very good at saying, 'Man, we're really strong on drug testing,'" he said. "And that's all they really want to be able to say and to do and to promote."


That helps explain how two school drug tests could miss Maneafaiga's steroid use. It's also possible that the random test came at an ideal time in Maneafaiga's steroid cycle.


Enforcement varies


The top steroid investigator at the U.S. Drug Enforcement Administration, Joe Rannazzisi, said he doesn't understand why schools don't invest in the same kind of testing, with the same penalties, as the NFL. The NFL has a thorough testing program for most drugs, though the league has yet to resolve a long-simmering feud with its players union about how to test for human growth hormone.


"Is it expensive? Of course, but college football makes a lot of money," he said. "Invest in the integrity of your program."


For a school to test all 85 scholarship football players for steroids twice a season would cost up to $34,000, Catlin said, plus the cost of collecting and handling the urine samples. That's about 0.2 percent of the average big-time school football budget of about $14 million. Testing all athletes in all sports would make the school's costs higher.


When schools ask Drug Free Sport for advice on their drug policies, Turpin said she recommends an immediate suspension after the first positive drug test. Otherwise, she said, "student athletes will roll the dice."


But drug use is a bigger deal at some schools than others.


At Notre Dame and Alabama, the teams that will soon compete for the national championship, players don't automatically miss games for testing positive for steroids. At Alabama, coaches have wide discretion. Notre Dame's student-athlete handbook says a player who fails a test can return to the field once the steroids are out of his system.


"If you're a strength-and-conditioning coach, if you see your kids making gains that seem a little out of line, are you going to say, 'I'm going to investigate further? I want to catch someone?'" said Anthony Roberts, an author of a book on steroids who says he has helped college football players design steroid regimens to beat drug tests.


There are schools with tough policies. The University of North Carolina kicks players off the team after a single positive test for steroids. Auburn's student-athlete handbook calls for a half-season suspension for any athlete caught using performance-enhancing drugs.


Wilfert said it's not up to the NCAA to determine whether that's fair.


"Obviously if it was our testing program, we believe that everybody should be under the same protocol and the same sanction," she said.


Fans typically have no idea that such discrepancies exist and players are left to suspect who might be cheating.


"You see a lot of guys and you know they're possibly on something because they just don't gain weight but get stronger real fast," said Orrin Thompson, a former defensive lineman at Duke. "You know they could be doing something but you really don't know for sure."


Thompson gained 85 pounds between 2001 and 2004, according to Duke rosters and Thompson himself. He said he did not use steroids and was subjected to several tests while at Duke, a school where a single positive steroid test results in a yearlong suspension.


Meanwhile at UCLA, home of the laboratory that for years set the standard for cutting-edge steroid testing, athletes can fail three drug tests before being suspended. At Bowling Green, testing is voluntary.


At the University of Maryland, students must get counseling after testing positive, but school officials are prohibited from disciplining first-time steroid users. Athletic department spokesman Matt Taylor denied that was the case and sent the AP a copy of the policy. But the policy Taylor sent included this provision: "The athletic department/coaching staff may not discipline a student-athlete for a first drug offense."


By comparison, in Kentucky and Maryland, racehorses face tougher testing and sanctions than football players at Louisville or the University of Maryland.


"If you're trying to keep a level playing field, that seems nonsensical," said Rannazzisi at the DEA. He said he was surprised to learn that what gets a free pass at one school gets players immediately suspended at another. "What message does that send? It's OK to cheat once or twice?"


Only about half the student athletes in a 2009 NCAA survey said they believed school testing deterred drug use.


As an association of colleges and universities, the NCAA could not unilaterally force schools to institute uniform testing policies and sanctions, Wilfert said.


"We can't tell them what to do, but if went through a membership process where they determined that this is what should be done, then it could happen," she said.


'Everybody around me was doing it'


Steroids are a controlled substance under federal law, but players who use them need not worry too much about prosecution. The DEA focuses on criminal operations, not individual users. When players are caught with steroids, it's often as part of a traffic stop or a local police investigation.


Jared Foster, 24, a quarterback recruited to play at the University of Mississippi, was kicked off the team in 2008 after local authorities arrested him for giving a man nandrolone, an anabolic steroid, according to court documents. Foster pleaded guilty and served jail time.


He told the AP that he doped in high school to impress college recruiters. He said he put on enough lean muscle to go from 185 pounds to 210 in about two months.


"Everybody around me was doing it," he said.


Steroids are not hard to find. A simple Internet search turns up countless online sources for performance-enhancing drugs, mostly from overseas companies.


College athletes freely post messages on steroid websites, seeking advice to beat tests and design the right schedule of administering steroids.


And steroids are still a mainstay in private, local gyms. Before the DEA shut down Alabama-based Applied Pharmacy Services as a major nationwide steroid supplier, sales records obtained by the AP show steroid shipments to bodybuilders, trainers and gym owners around the country.


Because users are rarely prosecuted, the demand is left in place after the distributor is gone.


When Joshua Hodnik was making and wholesaling illegal steroids, he had found a good retail salesman in a college quarterback named Vinnie Miroth. Miroth was playing at Saginaw Valley State, a Division II school in central Michigan, and was buying enough steroids for 25 people each month, Hodnik said.


"That's why I hired him," Hodnik said. "He bought large amounts and knew how to move it."


Miroth, who pleaded no contest in 2007 and admitted selling steroids, helped authorities build their case against Hodnik, according to court records. Now playing football in France, Miroth declined repeated AP requests for an interview.


Hodnik was released from prison this year and says he is out of the steroid business for good. He said there's no doubt that steroid use is widespread in college football.


"These guys don't start using performance-enhancing drugs when they hit the professional level," the Oklahoma City man said. "Obviously it starts well before that. And you can go back to some of the professional players who tested positive and compare their numbers to college and there is virtually no change."


Maneafaiga, the former Hawaii running back, said his steroids came from Mexico. A friend in California, who was a coach at a junior college, sent them through the mail. But Maneafaiga believes the consequences were nagging injuries. He found religion, quit the drugs and became the team's chaplain.


"God gave you everything you need," he said. "It gets in your mind. It will make you grow unnaturally. Eventually, you'll break down. It happened to me every time."


At the DEA, Rannazzisi said he has met with and conducted training for investigators and top officials in every professional sport. He's talked to Major League Baseball about the patterns his agents are seeing. He's discussed warning signs with the NFL.


He said he's offered similar training to the NCAA but never heard back. Wilfert said the NCAA staff has discussed it and hasn't decided what to do.


"We have very little communication with the NCAA or individual schools," Rannazzisi said. "They've got my card. What they've done with it? I don't know."


___


Associated Press writers Ryan Foley in Cedar Rapids, Iowa; David Brandt in Jackson, Miss.; David Skretta in Lawrence, Kan.; Don Thompson in Sacramento, Calif.;and Alexa Olesen in Shanghai, China; and researchers Susan James in New York and Monika Mathur in Washington contributed to this report.


___


Contact the Washington investigative team at DCinvestigations (at) ap.org.


Whether for athletics or age, Americans from teenagers to baby boomers are trying to get an edge by illegally using anabolic steroids and human growth hormone, despite well-documented risks. This is the first of a two-part series.


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Merry 'Cliffmas'! Chances for a Deficit Deal Dim













The outlook for a deal to avert the "fiscal cliff" by Christmas is increasingly grim, though lawmakers and the White House still have hope for a deficit-reduction compromise by the end of the year.


Republicans will move forward tonight with a vote to pass House Speaker John Boehner's so-called "Plan B option" – an extension of current tax rates for Americans making up to $1 million a year while replacing some pending automatic cuts to defense and domestic programs with other measures.


The step seeks to show Republicans acting to avoid an income tax hike on 99 percent of Americans in 2013, and leverage new pressure on President Obama in the ongoing talks for a broader "cliff" deal.


"Absent a balanced offer from the president, this is our nation's best option and Senate Democrats should take up both of these measures immediately," House Majority Leader Eric Cantor said today.


Obama has threatened to veto the legislation, calling it counterproductive and the cuts burdensome for the middle class. If the Senate were to consider the bill to stave off a looming tax hike, Democrats would surely amend it to enact more amicable terms.


"'Plan B'... is a multiday exercise in futility at a time when we do not have the luxury of exercises in futility," said White House spokesman Jay Carney.






Jacquelyn Martin/AP Photo













Outgoing Sen. Joe Lieberman Criticizes Colleagues for Putting Party Above Country Watch Video









President Obama Promises Action to Reduce Gun Violence Watch Video





The posturing on "plan B" has drawn focus away from a broader bargain on taxes, spending, entitlement reforms and other measures that had begun coming into focus earlier this week.


Obama and Boehner have not spoken since Monday, though staff-level talks have continued behind the scenes.


Senate Majority Leader Harry Reid said lawmakers would break for the Christmas holiday but return to Washington one week from today.


"If you look at Speaker Boehner's proposal and you look at my proposal, they're actually pretty close," Obama said Wednesday, appealing for a big "fair deal."


"It is a deal that can get done," he said. "But it cannot be done if every side wants 100 percent. And part of what voters were looking for is some compromise up here."


The latest offers exchanged by Obama and Boehner are roughly $450 billion apart, largely differing on where to draw the line for an income tax hike at the end of the year.


Obama wants to see rates rise on incomes above $400,000 a year, a concession from his earlier insistence on a $250,000 threshold. Boehner, who had opposed any tax rate increase, now says he could agree to a rate hike on earners of $1 million or more.


Both sides also disagree about the size of spending cuts and changes to entitlement programs.


Obama's plan would trim spending by $800 billion over a decade with half coming from Medicare and Medicaid. He has also agreed to limits on future cost-of-living increases for Social Security beneficiaries, something anathema to many Democrats.


But Boehner has said the cuts are insufficient. He seeks $1 trillion or more in spending reductions, citing entitlement programs as the primary drivers of U.S. deficits and debt.


"For weeks the White House said that if I moved on [tax] rates that they would make substantial concessions on spending cuts and entitlement reforms. I did my part. They've done nothing," Boehner said today.


"The real issue here, as we all know, is spending," he said. "I don't think that the White House has gotten serious about the big spending problem that our country faces."



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U.S. soldier referred to court martial over Afghan slayings


SEATTLE (Reuters) - A U.S. soldier accused of killing 16 Afghan villagers in two forays from his remote military camp has been referred to a court martial over the slayings and could face the death penalty, the military said on Wednesday.


The trial of Army Staff Sergeant Robert Bales is scheduled to take place at Joint Base Lewis-McChord in Washington state, but no date has been set, military officials said in a statement.


Military prosecutors are seeking the death penalty for Bales. They accuse him of gunning down the villagers - mostly women and children - over a five-hour period in March.


His lawyers have not set out an alternative theory to the prosecution's case, but have pointed out inconsistencies in pretrial testimony and highlighted incidents before the shooting where Bales lost his temper easily, possibly setting up an argument that he was suffering from post-traumatic stress disorder.


The shootings in Afghanistan's Kandahar province mark one of the deadliest civilian slaughters that the military has blamed on an individual U.S. soldier since the Vietnam War. The killings damaged already strained U.S.-Afghan relations.


The charges against Bales include 16 specifications of premeditated murder, six specifications of attempted murder and seven specifications of assault, the military said.


Bales is being held at Joint Base Lewis-McChord.


(Reporting by Laura L. Myers; Writing by Alex Dobuzinskis; Editing by Cynthia Johnston, Gary Hill)



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Obama calls for gun violence proposals within a month






WASHINGTON: President Barack Obama on Wednesday set up a task force to frame "concrete proposals" on ending mass shootings by next month and called for new laws, but denied he had been on "vacation" on gun control.

With trauma still raw after the Connecticut school massacre last week, Obama put Vice President Joe Biden in charge of an inter-agency effort on gun control and mental health, saying America had a "deep obligation" to act.

Obama, who failed to put political muscle behind greater gun control after previous mass slaughters, dismissed the notion that the task force would simply be a familiar, toothless Washington policy commission with little impact.

And he said killings of 20 children aged six and seven and six teachers and caregivers in the elementary school in Newtown were so horrific they should provide lawmakers with a potent incentive for action, even when the initial shock fades.

"I would hope that our memories aren't so short that what we saw in Newtown isn't lingering with us, that we don't remain passionate about it only a month later," Obama said at the White House.

"This is a team that has a very specific task to pull together real reforms right now.

"I will be putting forward very specific proposals. I will be talking about them in my State of the Union, and we will be working with interested members of Congress to try to get something done."

Obama urged the slow moving Congress to hold timely votes on banning military-style assault weapons like the one used by gunman Adam Lanza in Newtown and also on outlawing the sale of high-capacity ammunition clips.

He also called for new laws to ensure background checks for all gun purchases and signalled an effort to expand mental health care, in an effort to deter psychologically troubled people from turning to mass violence.

"We're going to need to make access to mental health at least as easy as access to a gun. We're going to need to look more closely at a culture that, all too often, glorifies guns and violence."

Biden has a history of framing crime legislation from his years in the Senate, has an affinity with law enforcement services, and also enjoys the kind of cordial links with many top Republicans in Congress that Obama lacks.

Obama, who comforted relatives of Newtown victims on Sunday, bristled when asked by a reporter whether he had been absent on gun control issues, following mass killings in Colorado, Arizona and Texas on his watch.

"I've been president of the United States, dealing with the worst economic crisis since the Great Depression, an auto industry on the verge of collapse, two wars. I don't think I've been on vacation."

Obama, who many conservatives believe wants to take away their guns, also said he supported the Second Amendment to the Constitution, which enshrines the right to bear arms in the United States.

"There is a big chunk of space between what, you know, the Second Amendment means and having no rules at all," he said.

Obama also called on the National Rifle Association, the most powerful gun lobby group which piles pressure on lawmakers over gun rights, to consider its priorities, before senior figures hold a news conference on Friday.

"The NRA is an organisation that has members who are mothers and fathers, and I would expect that they've been impacted by this as well, and hopefully they'll do some self-reflection."

The aftermath of the horrific shootings in Connecticut has prompted some pro-gun figures on Capitol Hill to admit that more needs to be done to regulate the sale and use of firearms.

But most evidence of shifting positions has been among Democrats, and there are signs that Republicans, especially those from rural, southern and conservative states may balk at new legislative action.

In another development Wednesday, Democratic Senator Jay Rockefeller announced a bill that would require a National Academy of Sciences assessment of links between violent games and violence.

Lanza was reportedly a fan of violent video games including "Dynasty Warriors."

- AFP/de



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Presidential pardon saved rapists the noose

NEW DELHI: The rising chorus to make rape an offence punishable by death penalty could be a fraught proposition. There have been at least four cases in the recent past where rapists awarded death penalty managed to escape the noose after the President commuted their sentence to life imprisonment.

These include a convict who raped and killed a five-year-old and another who tried to rape a teenager and killed her family in revenge when she resisted.

In most cases, courts follow the "rarest of rare" principle of criminal law giving death sentence to convicts who have committed murder. These four convicts were found guilty of not just rape but murder as well.

The most recent case was that of Uttar Pradesh's Bantu who was convicted of raping and killing a five-year-old girl. The trial court awarded him death which was confirmed by the HC and the apex court. On death row since June 2008, his mercy petition was accepted by President Pratibha Patil in June 2012.

Another convict Satish raped and murdered a six-year-old girl, Visakha, in Uttar Pradesh in 2001. His death sentence was commuted to life imprisonment by President Patil in May 2012.

The last accused hanged was Dhananjoy Chatterjee who was found guilty of rape and murder of a 14-year-old.

At present, there is one death row convict whose case has been pending since 1999. Dharam Pal from Haryana murdered five members of the family of a girl he had raped, helped by his brother. The trial court awarded them death and the Punjab and Haryana HC upheld the decision.

However, in March 1999, the apex court, while upholding Dharam Pal's death sentence, converted the sentence of the second accused into a life term. Pal's plea, filed in 1999, was rejected by the home ministry in 2000. The case was resubmitted to the President in 2005. The case came back to the home ministry after Pranab Mukherjee took over as President.

Rapists who escaped the noose:

Bantu raped and killed a five-year-old girl — June 2012

Satish raped and murdered a six-year-old girl — May 2012

Molai Ram & Santosh Yadav gang raped and murdered the 10-year-old daughter of a jailor — February 2011

Dharmender Singh and Narendra Yadav tried to rape a girl, then killed her family — June 2010

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Experts: Kids are resilient in coping with trauma


WASHINGTON (AP) — They might not want to talk about the gunshots or the screams. But their toys might start getting into imaginary shootouts.


Last week's school shooting in Connecticut raises the question: What will be the psychological fallout for the children who survived?


For people of any age, regaining a sense of security after surviving violence can take a long time. They're at risk for lingering anxiety, depression, post-traumatic stress disorder.


But after the grief and fear fades, psychiatrists say most of Newtown's young survivors probably will cope without long-term emotional problems.


"Kids do tend to be highly resilient," said Dr. Matthew Biel, chief of child and adolescent psychiatry at MedStar Georgetown University Hospital.


And one way that younger children try to make sense of trauma is through play. Youngsters may pull out action figures or stuffed animals and re-enact what they witnessed, perhaps multiple times.


"That's the way they gain mastery over a situation that's overwhelming," Biel explained, saying it becomes a concern only if the child is clearly distressed while playing.


Nor is it unusual for children to chase each other playing cops-and-robbers, but now parents might see some also pretending they're dead, added Dr. Melissa Brymer of the UCLA-Duke National Center for Child Traumatic Stress.


Among the challenges will be spotting which children are struggling enough that they may need professional help.


Newtown's tragedy is particularly heart-wrenching because of what such young children grappled with — like the six first-graders who apparently had to run past their teacher's body to escape to safety.


There's little scientific research specifically on PTSD, post-traumatic stress disorder, in children exposed to a burst of violence, and even less to tell if a younger child will have a harder time healing than an older one.


Overall, scientists say studies of natural disasters and wars suggest most children eventually recover from traumatic experiences while a smaller proportion develop long-term disorders such as PTSD. Brymer says in her studies of school shootings, that fraction can range from 10 percent to a quarter of survivors, depending on what they actually experienced. A broader 2007 study found 13 percent of U.S. children exposed to different types of trauma reported some symptoms of PTSD, although less than 1 percent had enough for an official diagnosis.


Violence isn't all that rare in childhood. In many parts of the world — and in inner-city neighborhoods in the U.S., too — children witness it repeatedly. They don't become inured to it, Biel said, and more exposure means a greater chance of lasting psychological harm.


In Newtown, most at risk for longer-term problems are those who saw someone killed, said Dr. Carol North of the University of Texas Southwestern Medical Center, who has researched survivors of mass shootings.


Friday's shootings were mostly in two classrooms of Sandy Hook Elementary School, which has about 450 students through fourth-grade.


But those who weren't as close to the danger may be at extra risk, too, if this wasn't their first trauma or they already had problems such as anxiety disorders that increase their vulnerability, she said.


Right after a traumatic event, it's normal to have nightmares or trouble sleeping, to stick close to loved ones, and to be nervous or moody, Biel said.


To help, parents will have to follow their child's lead. Grilling a child about a traumatic experience isn't good, he stressed. Some children will ask a lot of questions, seeking reassurance, he said. Others will be quiet, thinking about the experience and maybe drawing or writing about it, or acting it out at playtime. Younger children may regress, becoming clingy or having tantrums.


Before second grade, their brains also are at a developmental stage some refer to as magical thinking, when it's difficult to distinguish reality and fantasy. Parents may have to help them understand that a friend who died isn't in pain or lonely but also isn't coming back, Brymer said.


When problem behaviors or signs of distress continue for several weeks, Brymer says it's time for an evaluation by a counselor or pediatrician.


Besides a supportive family, what helps? North advises getting children back into routines, together with their friends, and easing them back into a school setting. Studies of survivors of the Sept. 11 terrorist attacks found "the power of the support of the people who went through it with you is huge," she said.


Children as young as first-graders can benefit from cognitive-behavioral therapy, Georgetown's Biel said. They can calm themselves with breathing techniques. They also can learn to identify and label their feelings — anger, frustration, worry — and how to balance, say, a worried thought with a brave one.


Finally, avoid watching TV coverage of the shooting, as children may think it's happening all over again, Biel added. He found that children who watched the 9/11 clips of planes hitting the World Trade Center thought they were seeing dozens of separate attacks.


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EDITOR'S NOTE — Lauran Neergaard covers health and medical issues for The Associated Press in Washington.


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