Italy election forecasts point to political gridlock

ROME (Reuters) - Conflicting early forecasts of the result of Italy's election on Monday raised the specter of deadlock in parliament that could paralyze a new government and re-ignite the euro zone crisis.

Officials from both center and left warned that such gridlock could make Italy ungovernable and force new elections.

Opinion polls have long pointed to the center-left of Pier Luigi Bersani winning the lower house, but projections from RAI state television showed Silvio Berlusconi's center right in front in the Senate - which has equal lawmaking power - but unable to form a majority.

RAI showed the center-left well short of a majority in the Senate even in coalition with Monti, who was seen slumping to only 19 out of 315 elected Senators against a massive 65 for the anti-establishment 5-Star Movement of comedian Beppe Grillo.

Senate votes are counted before the lower house.

The latest projections ran counter to earlier telephone polls that showed the center left taking a strong lead in the Senate as well as the lower house.

Italian financial markets took fright after rising earlier on hopes for a stable and strong center-left led government, probably backed by outgoing technocrat premier Mario Monti.

Such government is seen by investors as the best guarantee of measures to combat a deep recession and stagnant growth in the euro zone's third largest economy, which is pivotal to stability in the currency union.

Berlusconi's declared aim is to win enough power in the Senate to paralyze a center-left administration.

The benchmark spread between Italian 10-year bonds and their German equivalent widened from below 260 basis points to above 280 and the Italian share index lost all its previous gains.

"These projections suggest that we are heading for an ungovernable situation", said Mario Secchi, a candidate for Monti's centrist movement.

Stefano Fassina, chief economic official for Bersani's center-left, said: "The scenario from the projections we have seen so far suggest there will be no stable government and we would need to return to the polls."

The earlier telephone polls on Sky and Rai television after voting ended at 3 p.m. (1400 GMT/9 a.m. ET) had shown the center left 5-6 points ahead of the center right in both Senate and lower house, with Grillo taking third place.

Adding to the confusion, official results from more than 50 percent of polling stations showed the center-left ahead with 32.7 percent against 29.5 for the center-right in the Senate race. The partial official count is often not representative because of the order in which votes are counted regionally.

Italy's electoral laws guarantee a strong majority in the lower house to the party or coalition that wins the biggest share of the national vote.

However the Senate, elected on a region-by-region basis, is more complicated and the result will turn on four key battleground regions. Projections from LA 7 showed Berlusconi winning in three of them: Lombardy, Sicily and Campania.

A Sky television projection showed him strongly ahead in the rich northern region Lombardy, which returns the largest number of Senators, with 38.8 percent against 27.6 for the center left.

BITTER CAMPAIGN

A bitter campaign, fought largely over economic issues, has made some investors fear a return of the kind of debt crisis that took the euro zone close to disaster and brought the technocrat Monti to office, replacing the scandal-plagued Berlusconi, in 2011.

Monti helped save Italy from a debt crisis when Rome's borrowing costs were spiraling out of control, but the polls and projections suggested few Italians now see him as the savior of the country, in its longest recession for 20 years.

A surge in protest votes for Grillo's 5-Star Movement had raised uncertainty about the chances of a stable government that could fend off the danger of a renewed euro zone crisis.

Grillo's movement rode a huge wave of voter anger about both the pain of Monti's austerity program and a string of political and corporate scandals. It had particular appeal for a frustrated younger generation shut out of full-time jobs.

"I'm sick of the scandals and the stealing," said Paolo Gentile, a 49-year-old Rome lawyer who voted for 5-Star.

"We need some young, new people in parliament, not the old parties that are totally discredited."

Bad weather, including heavy snow in some areas, was thought to have hampered the turnout in Italy's first post-war election to be held in winter. This could have favored the center left, whose voters tend to be more committed than those on the right, which has strong support among older people.

Berlusconi, a 76-year-old media tycoon, pledged sweeping tax cuts and accused Monti of being a puppet of German Chancellor Angela Merkel in a media blitz that halved the lead of the center left in opinion polls since the start of the year.

Whatever government emerges will inherit an economy that has been stagnant for much of the past two decades and problems ranging from record youth unemployment to a dysfunctional justice system and a bloated public sector.

(Additional reporting by Stefano Bernabei, Steve Scherer, Gavin Jones and Giuseppe Fonte in Rome and Lisa Jucca in Milan; Writing by Barry Moody; Editing by Robin Pomeroy and Philippa Fletcher)

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US special forces told to leave key Afghan province

KABUL: Afghanistan's president has ordered US special forces to leave a strategic province as he seeks tighter control over Afghan militia, exacerbating tensions before the 2014 withdrawal of NATO troops.

Hamid Karzai on Sunday gave American special forces two weeks to pull out of Wardak, a hotbed of Taliban activity on the doorstep of Kabul, accusing Afghans they work with of torture and murder that has incited local hatred.

It remained unclear what led Karzai to issue the order, two US officials said. "We're not aware of any incident that would have generated this kind of response," one official, who spoke on condition of anonymity, told AFP.

At a news conference, spokesman for the US-led NATO mission Brigadier General Gunter Katz said: "We're looking at those allegations, we didn't find any evidence and we will talk to our colleagues and Afghan partners to find a solution."

The Pentagon confirmed that a special panel of Afghan officials and officers from the NATO-led International Security Assistance Force (ISAF) were looking into Karzai's allegations.

"We're trying to seek clarity from the government of Afghanistan," spokesman George Little told reporters.

Asked if the United States would pull out its elite special operations units from the province, Little said: "It's premature to speculate on what the outcome of our discussions would be."

Wardak is a deeply troubled flashpoint where a Chinook helicopter was shot down by the Taliban in August 2011, killing eight Afghans and 30 Americans, in the deadliest single incident for American troops in the entire war.

Analysts said the order underscored Kabul's growing distrust of international troops and their desire to control local militia, who are trained by the Americans but operate without government control in the war against the Taliban.

Relations between Karzai and Washington have long been troubled, and with the bulk of NATO's 100,000 combat soldiers due to leave and the Afghan president to step down next year, there is huge uncertainty about the future.

"It appears to be an on-the-spot, emotional decision, based on a long-standing frustration that there are forces... Afghan and international, that are uncontrollable," said Martine van Bijlert of the Afghanistan Analysts Network.

The New York Times quoted Afghan officials as saying the order was taken as a last resort after they had tried and failed to get the coalition to cooperate with an investigation into claims of murder, abduction and torture.

The presidency accused armed individuals working with US special forces of "harassing, annoying, torturing and even murdering innocent people".

It cited, for example, a student who was taken away at night from his home and two days later was found dead with torture wounds and his throat cut.

Kabul did not specify which groups were responsible, but the United States is understood to have trained a variety of local militias, a number of which reportedly operate beyond the control of the Afghan government.

Karzai's order was issued amid sensitive discussions over the size and role of a residual force that could remain in Afghanistan after 2014 to focus on training and counter-terrorism operations.

Kabul and Washington are still negotiating an agreement on the legal status that could allow an estimated 8,000 to 12,000 American troops to remain.

On February 16, Karzai also restricted Afghan forces from calling in NATO air strikes -- an important weapon in the fight against insurgents -- amid concern over civilian casualties.

Some say the latest order exemplifies a conflict that many Afghans feel towards foreign troops -- that they are needed to counter the Taliban, but that civilian casualties and detentions can also make them part of the problem.

A spokesman for Wardak's governor said local residents have complained for two and a half months about US special forces and "their illegal Afghan armed forces arresting, torturing and even killing villagers".

"We want our Afghan security forces to take control of this province and replace these US special forces," the spokesman, Ataullah Khogyani, told AFP.

In the neighbouring province of Ghazni, dozens of protesters shut down the Kabul-Kandahar highway for around three hours, accusing the US-trained Afghan Local Police (ALP) of harassment and beatings, officials and witnesses said.

The ALP is often accused of thuggery and operating outside the law, and its reputation was further damaged on December 24 when an officer shot dead five of his colleagues.

-AFP/ac

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Four IM men plotting strikes in India in return for ISI hospitality

NEW DELHI: They had fled to Pakistan to escape the long arm of the law in India. Now, they are plotting terror strikes on India with unflinching regularity as a trade-off for their own safety.

Four top Indian Mujahideen (IM) operatives - Riyaz Bhatkal, Iqbal Bhatkal, Amir Raza Khan and Fayyaz Kagzi - have been enjoying Pakistani spy agency ISI's hospitality with a quid pro quo of carrying out attacks on their homeland.

The rein of IM's terror machines is in the hands of the quartet, who have been operating through their commanders, including head of India operation Yasin Bhatkal, in various Indian cities.

Besides, there are others who keep shuttling between Pakistan (mainly Karachi) and Gulf countries (Saudi Arabia and UAE) on Pakistani passports. Their job is to establish contact with Indians who have been working in those countries, and are tasked with developing them as unsuspecting conduits to send remittances to India. The funds are used for creating sleeper cells for plotting future strikes.

They have been working in sync with the charter of the IM that was set up by ISI as an Indian proxy of the Pakistani terror outfit Lashkar-e-Taiba (LeT) to project to the world at large that terrorism in India is homegrown in both form and content. Consequently, most of the recruits in IM are Indians, who have been reporting to their bosses in Pakistan.

Indian security agencies, however, suspect that eight out of 15 key IM absconders continue to be in the country. "Couple of them must be in Nepal and keep coming to India," said a senior government official, adding India had shared dossiers on these fugitives with both Pakistan and Saudi Arabia.

Though Saudi Arabia had cooperated and helped deport three terrorists, including Abu Jundal (26\11 Mumbai terror attack accused) of LeT and Fasih Mohammed (IM operative), Pakistan has been in denial over the presence of Indian fugitives on its soil.

Faces of terror

Amir Reza Khan: The mobster of Kolkata (36) who along with the American Centre attack convict Aftab Ansari and two Bhatkal brother - Iqbal and Riyaz - had formed IM and been instrumental in carrying out a numbers of attacks across the country between 2005 and 2008. After fleeing India, he used to operate from Dubai, Riyadh and Oman. But, later he had shifted his base to Pakistan and largely confined to Karachi under ISI patronage after an Interpol Red Corner Notice (RCN) issued against him.

Riyaz Bhatkal: An engineer by profession, the Karnataka-born terrorist (36) had lived in Kurla, Mumbai, where he used to run a tannery business of his father before turning to the Students Islamic Movement of India (SIMI). He was known to Mohammed Sadique Israr Sheikh, a known criminal who worked for both Amir Reza and Aftab Ansari. He had fled India in 2008, when his name first cropped up in Bangalore and Ahmedabad blasts the same year.

Iqbal Bhatkal: Elder brother of Riyaz, Iqbal (44) is considered an IM ideologue, who was responsible for the August, 2007 serial blasts in Hyderabad along with his younger brother. He is a master in imparting instructions via electronic means to the terror outfit's cadres without leaving a trail. He is the one who has been supplying written\pictorial materials to the cadres to motivate them to carry out attacks on Indian soil.

Fayyaz Kagzi alias Abu Amir: He is the youngest (31) among the top four IM fugitives who have been running the show from Karachi. Originally a resident of Beed in Maharashtra, Kagzi was involved in a blast at Ahmedabad railway station. He had fled to Pakistan via Iran after his name cropped up in the Aurangabad arms haul case in 2006. Later, he had shifted his base to Saudi Arabia in 2008. He again moved to Pakistan when Saudi authorities had started cooperating with India in identifying and deporting Indian fugitives.

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Mediterranean-style diets found to cut heart risks

Pour on the olive oil, preferably over fish and vegetables: One of the longest and most scientific tests of a Mediterranean diet suggests this style of eating can cut the chance of suffering heart-related problems, especially strokes, in older people at high risk of them.

The study lasted five years and involved about 7,500 people in Spain. Those who ate Mediterranean-style with lots of olive oil or nuts had a 30 percent lower risk of major cardiovascular problems compared to those who were told to follow a low-fat diet but who in reality, didn't cut fat very much. Mediterranean meant lots of fruit, fish, chicken, beans, tomato sauce, salads, and wine and little baked goods and pastries.

Mediterranean diets have long been touted as heart-healthy, but that's based on observational studies that can't prove the point. The new research is much stronger because people were assigned diets to follow for a long time and carefully monitored. Doctors even did lab tests to verify that the Mediterranean diet folks were consuming more olive oil or nuts as recommended.

Most of these people were taking medicines for high cholesterol and blood pressure, and researchers did not alter those proven treatments, said one study leader, Dr. Ramon Estruch of Hospital Clinic in Barcelona.

But as a first step to prevent heart problems, "we think diet is better than a drug" because it has few if any side effects, Estruch said. "Diet works."

Results were published online Monday by the New England Journal of Medicine and were discussed at a nutrition conference in Loma Linda, Calif.

People in the study were not given rigid menus or calorie goals because weight loss was not the aim. That could be why they found the "diets" easy to stick with — only about 7 percent dropped out within two years. There were twice as many dropouts in the low-fat group than among those eating Mediterranean-style.

Researchers also provided the nuts and olive oil, so it didn't cost participants anything to use these relatively pricey ingredients. The type of oil may have mattered — they used extra-virgin olive oil, which is minimally processed and richer than regular or light olive oil in the chemicals and nutrients that earlier studies have suggested are beneficial.

The study involved people ages 55 to 80, just over half of them women. All were free of heart disease at the start but were at high risk for it because of health problems — half had diabetes and most were overweight and had high cholesterol and blood pressure.

They were assigned to one of three groups: Two followed a Mediterranean diet supplemented with either extra-virgin olive oil (4 tablespoons a day) or with walnuts, hazelnuts and almonds (a fistful a day). The third group was urged to eat a low-fat diet heavy on bread, potatoes, pasta, rice, fruits, vegetables and fish and light on baked goods, nuts, oils and red meat.

Independent monitors stopped the study after nearly five years when they saw fewer problems in the two groups on Mediterranean diets.

Doctors tracked a composite of heart attacks, strokes or heart-related deaths. There were 96 of these in the Mediterranean-olive oil group, 83 in the Mediterranean-nut group and 109 in the low-fat group.

Looked at individually, stroke was the only problem where type of diet made a big difference. Diet had no effect on death rates overall.

The Mediterranean diet proved better even though its followers ate about 200 calories more per day than the low-fat group did. The study leaders now are analyzing how each of the diets affected weight gain or loss and body mass index.

The Spanish government's health research agency initiated and paid for the study, and foods were supplied by olive oil and nut producers in Spain and the California Walnut Commission. Many of the authors have extensive financial ties to food, wine and other industry groups but said the sponsors had no role in designing the study or analyzing and reporting its results.

Rachel Johnson, a University of Vermont professor who heads the American Heart Association's nutrition committee, said the study is very strong because of the lab tests to verify oil and nut consumption and because researchers tracked actual heart attacks, strokes and deaths — not just changes in risk factors such as high cholesterol.

"At the end of the day, what we care about is whether or not disease develops," she said. "It's an important study."

Rena Wing, a weight-loss expert at Brown University, noted that researchers provided the oil and nuts, and said "it's not clear if people could get the same results from self-designed Mediterranean diets" — or if Americans would stick to them more than Europeans who are used to such foods.

Dr. George Bray of the Pennington Biomedical Research Center in Baton Rouge, La., said he would give the study "a positive — even glowing — comment" and called it "the best and certainly one of the largest prospective dietary trials ever done."

"The data are sufficiently strong to convince me to move my dietary pattern closer to the Mediterranean Diet that they outline," he added.

Another independent expert also praised the study as evidence diet can lower heart risks.

"The risk reduction is close to that achieved with statins," cholesterol-lowering drugs, said Dr. Robert Eckel, a diet and heart disease expert at the University of Colorado.

"But this study was not carried out or intended to compare diet to statins or blood pressure medicines," he warned. "I don't think people should think now they can quit taking their medicines."

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Online:

Journal: http://www.nejm.org

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Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP

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Secret Vatican Dossier for 'Pope's Eyes Only'

Feb 25, 2013 9:05am

ROME – Pope Benedict XVI decided to keep secret the contents of an investigative report on the “Vatileaks” scandal, ruling that the only person who will get to see it will be the next pope.

The top secret dossier details the findings of an internal investigation the pope launch last April into the so-called Vatileaks affair, in which Benedict’s former butler leaked confidential documents stolen from the papal chambers.

Italian newspapers have claimed — without attribution — that the investigation revealed a sex and blackmail scandal inside the curia.

The Vatican spokesman today underscored that the contents of the dossier are known only to the pope and his investigators, three elderly prelates whom the Italian papers have nicknamed “the 007 cardinals.”

Pope Benedict met today with Cardinals Julian Herranz of Spain, Jozef Tomko of Slovakia, and Salvatore De Giorgi of Sicily in a private audience.

According to the Vatican, the pope thanked them for their work and expressed satisfaction with their investigation.

“Their work made it possible to detect, given the limitations and imperfections of the human factor of every institution, the generosity and dedication of those who work with uprightness and generosity in the Holy See,” read a Vatican statement.

The Vatican statement pointedly added: “The Holy Father has decided that the acts of this investigation, known only to himself, remain solely at the disposition of the new pope.”

Many here had expected the investigating cardinals, who are too old to participate in the conclave, would brief the voting cardinals about their findings.

Today Vatican officials clarified the investigating cardinals will be free to discuss their investigation with the other cardinals, as the voting members of the conclave seek to understand the challenges the next pope will face.

But the dossier itself will remain “For the Pope’s Eyes Only.”

SHOWS: World News

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Gloomy Italians vote in election crucial for euro zone

ROME (Reuters) - Italy voted on Sunday in one of the most unpredictable elections in years, with many voters expressing rage against a discredited elite and doubt that a government will emerge strong enough to combat a severe economic crisis.

"I am pessimistic. Nothing will change," said Luciana Li Mandri, 37, as she cast a ballot in the Sicilian capital Palermo on the first of two days of voting that continues on Monday.

"The usual thieves will be in government."

Her gloom reflected the mood across Italy, where many voters said they thought the new administration would not last long, just the opposite of what Italy needs to combat the longest slump in 20 years, mounting unemployment and a huge public debt.

The election is being closely watched by investors whose memories are fresh of a debt crisis which forced out scandal-plagued conservative premier Silvio Berlusconi 15 months ago and saw him replaced by economics professor Mario Monti.

"I'm not confident that the government that emerges from the election will be able to solve any of our problems," said Attilio Bianchetti, a 55-year-old building tradesman in Milan.

Underlining his disilluion with the established parties, he voted for the 5-Star Movement of comic Beppe Grillo.

An iconclastic, 64-year-old Genoese, Grillo has screamed himself hoarse with obscenity-laced attacks on politicians that have channeled the anger of Italians, especially a frustrated young generation hit by record unemployment.

"He's the only real new element in a political landscape where we've been seeing the same faces for too long," said Vincenzo Cannizzaro, 48, in Palermo.

Opinion polls give the centre-left coalition of Pier Luigi Bersani a narrow lead but the result has been thrown open by the prospect of a huge protest vote against Monti's painful austerity measures and rage at a wave of corruption scandals.

A weak government could usher in new instability in the euro zone's third largest economy and cause another crisis of confidence in the European Union's single currency.

Television tycoon Berlusconi, showing off unrivalled media skills and displaying extraordinary energy for a man of 76, has increased uncertainty over the past couple of months by halving the gap between his centre-right and Bersani.

"I am pessimistic. There is such political fragmentation that we will again have the problem of ungovernability" said Marta, a lawyer voting in Rome who did not want to give her family name. "I fear the new government won't last long."

Another Roman voter, lab technician Manila Luce, 34, said: "I am voting Grillo and I hope a lot of people do. Because it's the only way to show how sick to the back teeth we are with the old parties."

Voting continues until 10 p.m. (4 p.m. EST) and resumes on Monday at 7 a.m. Exit polls will be published shortly after polls close at 3 p.m. on Monday. Full official results are expected by early Tuesday.

Snow in the north was expected to last into Monday and could discourage some of the 47 million eligible voters. Authorities said they were prepared for the weather and in the central city of Bologna roads were cleared of snow before voting started.

TOPLESS FEMINISTS

Several bare-breasted women protested against Berlusconi when he voted in Milan. They were bundled away by police.

The four-time premier, known for off-color jokes and a constant target of feminists, is on trial for having sex with an underage prostitute during "bunga bunga" parties at his villa.

Most experts expect a coalition between Bersani and Monti to form the next administration, but whatever government emerges will have to try to reverse years of failure to revitalize one of the most sluggish economies in the developed world.

The widespread despair over the state of the country, where a series of corruption scandals has highlighted the stark divide between a privileged political elite and millions of ordinary Italians struggling to make ends meet, has left deep scars.

"It's our fault, Italian citizens. It's our closed mentality. We're just not Europeans," said voter Li Mandri in Palermo.

"We're all about getting favors when we study, getting a protected job when we work," she said. "That's the way we are and we can only be represented by people like that as well."

ECONOMIC AGENDA

Even if Bersani wins as expected, Analysts are divided over whether he will be able to form a stable majority that can force through sweeping economic reforms.

His centre-left is expected to have firm control of the lower house, thanks to rules that give a strong majority to whichever party wins the most votes nationally.

But a much closer battle will be fought for the Senate which is elected on a regional basis and which has equal law making powers to the chamber.

Berlusconi has clawed back support by promising to repeal Monti's hated new housing tax, the IMU, and to refund the money. He relentlessly attacked what he called the "Germano-centric" policies of the former European Union commissioner.

Think-tank consultant Mario, 60, said on his way to vote in Bologna that Bersani's Democratic Party was the only group serious enough to repair the economy: "They're not perfect," he said. "But they've got the organization and the union backing that will help them push through structural reforms."

Despite Berlusconi's success, Grillo has tapped into the same public frustration as the conservative tycoon and pollsters say his 5-Star Movement of political novices could overtake the centre-right to take second place in the vote.

Rivals have branded Grillo a threat to democracy - a vivid image in a country ruled by fascists for two decades until World War Two. Several voters who spoke to Reuters said Grillo was not the answer because of his lack of concrete policies and the inexperience of those who will sit in parliament for 5-Star.

"Grillo is a populist and populism doesn't work in a democracy," said retired notary Pasquale Lebanon, 76, as he voted for Bersani's Democratic Party in Milan.

"I'm very worried. There seems to be no way out from a political point of view, or for being able to govern," said Calogero Giallanza, a 45-year-old musician in Rome as he also voted for Bersani.

"There's bound to be a mess in the Senate because, as far as I can see the 5-Star Movement is unstoppable."

(Additional reporting by Cristiano Corvino, Lisa Jucca, Jennifer Clark, Matthias Baehr, Jennifer Clark and Sara Rossi in Milan, Stephen Jewkes in Bologna, Wladimir Pantaleone in Palermo, Stefano Bernabei and Massimiliano Di Giorgio in Rome; Writing by James Mackenzie and Barry Moody; Editing by Alastair Macdonald)

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Calls mount for US action against Chinese hack attacks

WASHINGTON: Calls mounted Sunday for stiffer US action against Beijing for cyber spying and massive theft of US industrial secrets, allegedly by the Chinese military.

Mike Rogers, the chairman of the House Intelligence Committee, said it was "beyond a shadow of a doubt" that the Chinese military was behind a growing wave of hacking attacks on US businesses and institutions.

"They use their military to steal intellectual property from American businesses and European businesses, repurpose it, and compete in the international market against the United States," he said.

"It's unprecedented," he said on ABC's This Week. "And I'll tell you, it's bad as I have ever seen it. It's getting worse. Why? There's no consequence for it."

In the most detailed account yet of the cyber spying, a report this week by the Mandiant security firm said it traced back attacks by one group of hackers to a building on the outskirts of Shanghai that houses a unit of the People's Liberation Army.

The report said the hackers, known as "APT1" or "Comment Crew," had stolen data from at least 141 organisations across 20 industries.

Last month the New York Times and other American media outlets reported they had come under hacking attacks from China, and a US congressional report last year named the country as "the most threatening actor in cyberspace."

China has called the charges "groundless," and state media has accused Washington of scapegoating Beijing to deflect attention from US economic problems.

Eliot Engel, the top Democrat in the House Foreign Affairs Committee, said US lawmakers raised the issue with top Chinese officials during a recent visit to Beijing.

"And they just let it roll off their back. They pooh-pooh it. They don't admit to it," he said on ABC.

But he said it was "fundamental" to the US relationship with the Chinese.

"I think we have to make it very clear to them that this cannot be business as usual. If they're going to continue to do this to the extent that they're doing it, there's a price to pay," he said.

Rogers drew a distinction between cyber espionage to steal state secrets, which he said all states engage in, and the theft of blueprints and industrial secrets from US companies for economic reasons.

He said the United States should respond by "indicting bad actors," and suggested that Washington deny visas to individuals in China who are involved in the hacking and their families.

"I'm arguing let's start the indictment process to send a message to China that you cannot, if you want to be an international player, you can't act like a thief in the night," he said.

- AFP/jc

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PM expresses solidarity with blast victims

HYDERABAD: Prime Minister Manmohan Singh on Sunday expressed solidarity with the people of the city, shaken by the twin bomb blasts in Dilsukhnagar on Thursday. After visiting the blast site and the hospitals where the injured were being treated, the PM lauded the people for refusing to be provoked.

Singh, who flew to Hyderabad from Delhi in a special IAF plane, paid a visit to Disukhnagar following which he met the injured at Omni and Yashoda Hospitals, and assured the families of the victims all help from the centre. "I have come to share the grief of the people of Hyderabad. I express condolence for the families of the bereaved and wish speedy recovery for the injured," Singh said after meeting the blast victims at the hospitals.

Before leaving for Delhi, the PM held a review meeting with chief minister N Kiran Kumar Reddy and his cabinet ministers during which DGP V Dinesh Reddy briefed him about the progress of the investigation into the case. The police chief is understood to have told the PM that six investigative teams have been formed and that the case would be cracked at the earliest.

Singh was received on Sunday morning at Begumpet airport by Andhra Pradesh Governor ESL Narasimham, the Chief Minister and his cabinet colleagues.

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FDA approves new targeted breast cancer drug

WASHINGTON (AP) — The Food and Drug Administration has approved a first-of-a-kind breast cancer medication that targets tumor cells while sparing healthy ones.

The drug Kadcyla from Roche combines the established drug Herceptin with a powerful chemotherapy drug and a third chemical linking the medicines together. The chemical keeps the cocktail intact until it binds to a cancer cell, delivering a potent dose of anti-tumor poison.

Cancer researchers say the drug is an important step forward because it delivers more medication while reducing the unpleasant side effects of chemotherapy.

"This antibody goes seeking out the tumor cells, gets internalized and then explodes them from within. So it's very kind and gentle on the patients — there's no hair loss, no nausea, no vomiting," said Dr. Melody Cobleigh of Rush University Medical Center. "It's a revolutionary way of treating cancer."

Cobleigh helped conduct the key studies of the drug at the Chicago facility.

The FDA approved the new treatment for about 20 percent of breast cancer patients with a form of the disease that is typically more aggressive and less responsive to hormone therapy. These patients have tumors that overproduce a protein known as HER-2. Breast cancer is the second most deadly form of cancer in U.S. women, and is expected to kill more than 39,000 Americans this year, according to the National Cancer Institute.

The approval will help Roche's Genentech unit build on the blockbuster success of Herceptin, which has long dominated the breast cancer marketplace. The drug had sales of roughly $6 billion last year.

Genentech said Friday that Kadcyla will cost $9,800 per month, compared to $4,500 per month for regular Herceptin. The company estimates a full course of Kadcyla, about nine months of medicine, will cost $94,000.

FDA scientists said they approved the drug based on company studies showing Kadcyla delayed the progression of breast cancer by several months. Researchers reported last year that patients treated with the drug lived 9.6 months before death or the spread of their disease, compared with a little more than six months for patients treated with two other standard drugs, Tykerb and Xeloda.

Overall, patients taking Kadcyla lived about 2.6 years, compared with 2 years for patients taking the other drugs.

FDA specifically approved the drug for patients with advanced breast cancer who have already been treated with Herceptin and taxane, a widely used chemotherapy drug. Doctors are not required to follow FDA prescribing guidelines, and cancer researchers say the drug could have great potential in patients with earlier forms of breast cancer

Kadcyla will carry a boxed warning, the most severe type, alerting doctors and patients that the drug can cause liver toxicity, heart problems and potentially death. The drug can also cause severe birth defects and should not be used by pregnant women.

Kadcyla was developed by South San Francisco-based Genentech using drug-binding technology licensed from Waltham, Mass.-based ImmunoGen. The company developed the chemical that keeps the drug cocktail together and is scheduled to receive a $10.5 million payment from Genentech on the FDA decision. The company will also receive additional royalties on the drug's sales.

Shares of ImmunoGen Inc. rose 2 cents to $14.32 in afternoon trading. The stock has ttraded in a 52-wek range of $10.85 to $18.10.

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Pistorius' Brother Facing Own Homicide Trial

The attorney for Oscar Pistorius' family said today that the Olympian's brother is facing a culpable homicide charge relating to a 2008 road accident in which a motorcyclist was killed.

Carl Pistorius, who sat behind his younger brother, Oscar, every day at his bail hearing, will now face his own homicide trial for the accident five years ago, which his attorney, Kenny Oldwage, said he "deeply regrets."

Carl Pistorius is charged with culpable homicide, which refers to the unlawful negligent killing of another person. The charges were initially dropped, but were later reinstated, Oldwage said in a statement.

Full Coverage: Oscar Pistorius Case

Pistorius quietly appeared in court on Thursday, one day before his Paralympic gold-medalist brother was released on bail, Oldwage said. His next appearance is scheduled for the end of March.

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'Blade Runner' Murder Charges: Oscar Pistorius Out on Bail Watch Video

Oscar Pistorius Granted Bail in Murder Case Watch Video

It was the latest twist in a case that has drawn international attention, after 26-year-old Oscar Pistorius, a double amputee who ran in both the 2012 Olympic and Paralympic games, was charged with the premeditated murder of his model girlfriend, Reeva Steenkamp.

On Saturday, Carl Pistorius' Twitter handle was hacked, according to a family spokeswoman, prompting the Pistorius family to cancel their social media accounts.

Steenkamp's parents speak about the Valentine's Day shooting that ended their daughter's life in a sit-down interview on South African television tonight.

On Saturday, the model's father, Barry Steenkamp, told the Afrikaans-language Beeld newspaper that Pistorius will have to "live with his conscience" and will "suffer" if his story that he shot Steenkamp because he believed she was an intruder is false.

RELATED: Oscar Pistorius Case: Key Elements to the Murder Investigation

After a four-day long bail hearing, Pistorius was granted bail Friday by a South African magistrate.

The court set bail at about $113,000 (1 million rand) and June 4 as the date for Pistorius' next court appearance.

Pistoriuis is believed to be staying at his uncle's house as he awaits trial. As part of his bail conditions, Pistorius must give up all his guns, he cannot drink alcohol or return to the home where the shooting occurred, and he must check in with a police department twice a week.

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